Welcome to Whole Genome Searcher!
Did you know you can get valuable medical information from a simple liquid biopsy?
We have worked in the past year to create an innovative algorithm to search DNA sequences to get clinically valuable information to help diagnose patients (a non-invasive “liquid biopsy“). Examples are the presence of bacteria, viruses and somatic (non inheritable) cancer mutations. This first (free) version of the tool has now gone live on this page.
Analyze patients with ease: from a blood sample, detect viruses, bacteria and search for somatic cancer markers. Or from a gut sample, get the patients´ gut microbiome composition (a mouth swap will give the the oral microbiome). This tool will take a DNA file and analyze the DNA data that was not used to assemble the regular human chromosomes. That may include non-human DNA or human DNA with large somatic mutations. The result of the DNA search will be a report of viral, bacterial and fungal sequences present. The second search in this tool will look for possibly carcinogenic mutations.
Whole Genome Sequencing (WGS) captures all DNA fragments (“reads”) present in a biological sample. If this sample is human, most of these reads will be human and used to assemble the human chromosomes. If a whole genome sequence is available, it is possible to extract far more medical information than just the inheritable chromosomes.
Usually, bacterial, viral, or fungal DNA is present too, but this data is not often used clinically. These unused reads can offer valuable diagnostic insights, also depending on where the sample came from:
- Intestinal or oral samples may reveal microbiome imbalances (i.e. which bacteria were present?)
- Blood samples may uncover circulating pathogens (i.e. viruses)
Additionally, blood can contain cell-free DNA (cfDNA), released by dying (f.e. cancer) cells. Analyzing cfDNA may therefore help search for cancer-associated mutations and better understand disease progression.
If you have a .bam (or .fastQ) file, you can upload it in this tool straight-away. If you do not have a sequence (.bam) file available, you can order a sequence at a sequencing service. Please note that there are cost associated with the test and it may take at least a few weeks for the results to become available.
Privacy First — Your Data Is Never Stored
We take patient privacy and data protection very seriously.
When you upload a DNA file (e.g. BAM or FASTQ), it is used only for analysis.
As soon as the analysis is complete, the file is automatically and permanently deleted from our servers.
We do not:
- Store or archive any individual DNA data
- Use uploaded files for AI training, research, or any secondary purpose
Our system is designed to handle data transiently, ensuring full confidentiality.