To use the analysis tool on wgsearcher.com, you need to upload a Whole Genome Sequence (WGS), contained in a .BAM file. If you don’t have a BAM file, you’ll need to have DNA sequenced first by a professional service. Below, we list six companies that offer whole-genome sequencing (WGS) DNA sequencing services. Always consult your healthcare provider to determine the best sequencing option for your care needs!

Some DNA Sequencing Companies:

The companies listed above are external providers known to offer DNA sequencing services. wgsearcher.com does not endorse, partner with, or guarantee the quality, accuracy, or suitability of these services for your specific needs. We recommend thoroughly researching each provider and consulting with a qualified medical professional before proceeding with DNA sequencing. Ensure the provider complies with relevant privacy regulations, such as HIPAA, to protect your genetic information. The cost of the sequencing will be approximately $300-$500

Choosing the Right Sample Type

The type of sample you provide for sequencing determines the kind of genetic or microbial information you’ll receive. Discuss with your healthcare provider to ensure the sample matches your analysis goals:

  • Mutation Analysis: For searching for cancer-related mutations, a blood sample is typically best, as it can capture circulating tumor DNA (ctDNA) or other biomarkers relevant to cancer.
  • Gut Microbiome Analysis: To study the microbial content of your intestines, a stool sample is required, as it reflects the microbiome in the gut.
  • Oral Microbiome Analysis: A mouth swab (e.g., cheek or saliva) provides information about the microbiome in your mouth, not any gut mutations.

When requesting a test, confirm with the sequencing company that they can process the appropriate sample type for your needs and provide the data in BAM file format.

What to do next

To generate a BAM file for use with wgsearcher.com, follow these steps:

  1. Request a Test from a Sequencing Company: Contact one of the listed companies and request a whole-genome sequencing (WGS) test. Confirm that the company can deliver the sequencing data in a BAM file format, which is typically standard for WGS, and that they can process the appropriate sample type (e.g., blood for searching for cancer mutations). Also confirm their delivery times as some companies may take a long time.
  2. Receive a Sample Collection Kit: The sequencing company will send you a kit, typically containing a swab, saliva tube, blood collection tool, or stool collection container, depending on the test, along with instructions.
  3. Take a Sample: Follow the kit’s instructions to collect your sample (e.g., blood, stool, or mouth swab) based on the type of analysis you need.
  4. Send the Sample Back: Return the collected sample to the sequencing company using the provided packaging and shipping instructions.
  5. Sequencing Process: The company will sequence your sample using advanced technology, such as next-generation sequencing (NGS), to generate your genomic or microbial data.
  6. Notification of Results: The sequencing company will notify you when your sequence is ready, typically via email.
  7. Download the BAM File: Access your sequencing data through the company’s portal or by request, ensuring you download the data in BAM file format.
  8. Upload to wgsearcher.com: Visit wgsearcher.com, upload your BAM file to our tool, and receive your cancer mutation analysis.

Important Notes

  • Medical Guidance: Always consult your healthcare provider before ordering DNA sequencing to ensure it aligns with your care plan.
  • Data Privacy: Verify that the sequencing company complies with privacy regulations, such as HIPAA, to protect your genetic information.
  • File Format Confirmation: Double-check with the provider that the sequencing data will be delivered as a BAM file.

For questions or support, contact us at support@wgsearcher.com.

Leave a comment if you have any experience with the companies!